1. Siberian ginseng
Although there are no clinical trials showing Siberian ginseng is effective for fatigue, clinical experience finds it helps and we recommend it to combat that run-down feeling. The method of preparation varies among brands, so check the box for the exact dose. Don’t take it after 3 p.m. or it could interfere with your sleep. If you have diabetes or high blood pressure, you’ll want to stay away from ginseng.